Subtotal Pancreatectomy for Congenital Hyperinsulinism: Our Experience and Review of Literature

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Successful treatment of a newborn with congenital hyperinsulinism having a novel heterozygous mutation in the ABCC8 gene using subtotal pancreatectomy

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CONTEXT Congenital hyperinsulinism (CHI), the commonest cause of persistent hypoglycaemia, has two main histological subtypes: diffuse and focal. Diffuse CHI, if medically unresponsive, is managed with near-total pancreatectomy. Post-pancreatectomy, in addition to persistent hypoglycaemia, there is a very high risk of diabetes mellitus and pancreatic exocrine insufficiency. SETTING Internatio...

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ژورنال

عنوان ژورنال: Indian Journal of Surgery

سال: 2013

ISSN: 0972-2068,0973-9793

DOI: 10.1007/s12262-013-0999-9